Keep up with the latest INSIGNIA news, including NHS site approvals, study recruitment news and scientific meetings that our study team will be attending.


  • 9-12th July 2016 EACR24: The 24th Biennial Congress of the European Association for Cancer Research, Manchester, UK. Dr Serena Nik-Zainal will present on "Advances in mutation signatures revealed through analyses of 560 whole breast cancer genomes" within the Breakthrough Tools in Cancer Genetics symposium.
  • 26-29th June 2016 UKEMS Annual Conference: A COMSIG consortium-sponsored symposium "Causes of Mutational Signatures" will take place at the 39th Annual Meeting of the United Kingdom Environmental Mutagen Society. The meeting takes place in London, UK.
  • 5-10th June 2016 Dr Serena Nik-Zainal will be speaking about "Advances in the Understanding of Signatures of Mutagenesis in Human Somatic Cells" at the 2016 Mutagenesis and Genome Alterations Gordon Research Conference, Girona, Spain.
  • 28th April 2016 INSIGNIA has now recruited its 50th participant! Many thanks to all involved.
  • 18th April 2016 Dr Serena Nik-Zainal will be presenting at the 10th Quinquennial Conference on Responses to DNA damage: from molecule to disease, Egmond aan Zee, The Netherlands, April 17-22. Dr Nik-Zainal's talk is entitled "Recent advances in mutational signatures identified in human somatic cells".
  • 29th February 2016: Dr Serena Nik-Zainal has been invited to speak at the annual Double Helix Day held at Cold Spring Harbor Laboratory. The theme of the 2016 celebrations is DNA Damage, Repair & Mutation. Dr Nik-Zainal's talk is entitled "The genome: An archaeological record of mutational processes". Dr Nik-Zainal will be presenting alongside other invited speakers that include James Watson, Leona Samson, Thomas Kunkel and James Haber.
  • 21st January 2016: Dr Serena Nik-Zainal will be presenting at the Festival of genomics, London on the 21st January at 2.00pm. The seminar will be presented in the Cancer Data Analysis stream and is entitled ‘My cancer genome’. The Festival of Genomics takes place 19th-21st January at the ExCel London Exhibition and Convention Centre.


  • 4th December 2015: Dr Serena Nik-Zainal presented a talk entitled ‘INSIGNIA’ at the Cancer Genetics Group Winter Meeting, University College London.
  • 11th November 2015: Dr Serena Nik-Zainal presented a seminar at Guy’s and St Thomas’ NHS Foundation Trust, London.
  • 13th October 2015: The Australian Genomic Technologies Association Conference was held in Hunter Valley, New South Wales, Australia, 11th-14th October 2015. Dr Serena Nik-Zainal gave a keynote lecture entitled 'Advances in the understanding of mutational signatures in human somatic cells’.
  • 6 October 2015: Dr Serena Nik-Zainal presented a seminar at the Duke NUS Medical School, Singapore.
  • 29th June 2015: The EACR Conference Series 2015 - Cancer Genomic, was held in Cambridge 28th June-1st July. Dr Serena Nik-Zainal presented a talk on 29th June.
  • 13th May 2015: The EACR-OECI Joint Training course, Molecular Pathology Approach to Cancer was held 11th-13th May 2015 in Amsterdam, the Netherlands. Dr Serena Nik-Zainal presented a talk on13th May.
  • 21st April 2015: The American Association for Cancer Research Annual Meeting was held 18th-22nd April, Philadelphia, USA. Dr Serena Nik-Zainal presented on 21st April. The title of her talk was ‘Whole genome sequencing readouts of deficiencies in DNA repair pathways’.
  • 17 February 2015: Dr Serena Nik-Zainal presented a talk at the 10th International Cancer Genome Consortium Scientific Workshop, Verona on 17th February.
  • 29 January 2015: Dr Serena Nik-Zainal presented a talk at the Genomic Medicine for Clinicians Training Course, Wellcome Trust Genome Centre, Hinxton, Cambridge.


  • 7th November 2014: Dr Serena Nik-Zainal will be giving the William Bate Hardy Prize lecture on Monday 10th November at 6.00pm, Department of Chemistry, Cambridge. The lecture is entitled 'The Changing Genome: Signatures of Mutagenesis in Human Cells'.

    The Cambridge Philosophical Society awards a William Bate Hardy Prize once every three years for the best original memoir, investigation or discovery by a member of the University of Cambridge in connection with Biological Sciences that may have been published during the three years immediately preceding. Download poster.
  • 3rd November 2014: Dr Serena Nik-Zainal has been awarded the Cancer Research UK 2014 Future Leaders in Cancer Research Prize. The prize-giving ceremony took place at the NCRI Conference in Liverpool.

    Each year, Cancer Research UK awards a set of prizes to honour the achievements of scientists and clinicians in the cancer research community by recognising their contributions to beating cancer. Dr Serena Nik-Zainal was awarded this prize to recognise that her past and present work will significantly contribute to the understanding of how mutations arise during tumour development.
  • 13th August 2014: The British Society for Genetic Medicine Annual Meeting will be held in Liverpool 22nd-24th Sept 2014. Dr Serena Nik-Zainal will be presenting during the Practical Research in Genetic Healthcare session on Tues 23rd Sept. The title of the talk will be 'INSIGNIA: Investigating mutation signatures in genetic disorders.'
  • 21st July 2014: INSIGNIA has received ethical approval from the Scotland A REC Committee, and has been approved for the purposes of the Adults with Incapacity (Scotland) Act 2000.
  • 16th July 2014: Dr Serena Nik-Zainal presented the INSIGNIA study to clinicians at St. George's NHS Trust
  • 27th June 2014: INSIGNIA study team members attended The Genetics Research Forum Study Day, London
  • 18th March 2014: Recruitment to INSIGNIA has begun!


  • 20th Nov 2013: INSIGNIA has received ethical approval from the NRES Committee East of England - Norfolk

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